Warka Xanaalaha: Horumarinta hargabka Avian Cilmi baarista

Wararka 01

Ogaanshaha koowaad ee H4N6-na waayeel ee hargabka hargabka Avian virus ee Ducks-ka Mallard (anas platyrhynchos) ee Israel

AVISKI LULLIN, Nikki Thie, Irina Shkoda, Luigal Farnoulous, Yigal Farnoulous, Roni Knonoushi, Roni Khone Farnooushi, Roni The-Geune Mentz, Pauline L Kamath, rairi L Kamath, Ran Nathan

PMID: 356875561; doi: 10.11111 / tbed.14610

Fayraska hargabka avian (AIV) wuxuu khatar daran ku hayaa xayawaanka iyo caafimaadka aadanaha adduunka oo dhan. Maaddaama loo gudbiyo AIV Wordfowl oo adduunka oo dhan ah, baaraya baahinta AIV ee dadka duurjoogta ah ay muhiim u tahay fahamka gudbinta unugyada iyo saadaalinta cudurrada ka dillaaca xayawaanka guryaha iyo aadanaha. Daraasaddan, H4N6 Subtype AIV ayaa markii ugu horeysay laga soo qaatay tusaalayaasha caagga ah ee shaandhada cagaaran ee duurjoogta ah (anas platrhynchos) reer binu Israa'iil). Natiijooyinka phylotenetic of phylogenotic of Ha hiddo-wadaha ayaa soo jeedinaya in culeyskan uu si dhow ula xiriiro jaallooyinka Yurub iyo Aasiya. Iyada oo Israa'iil ay ku taallo wadada Arctic-Archic-Africaric-ka ee Arctic, waxaa loo malaynayaa in cadaadiska laga yaabo in ay soo saartay shimbiraha galka. Falanqaynta phylotenetic ee hiddo-wadayaasha gudaha ah H4N6-naadka H4N6 ee AIV wuxuu leeyahay sicirka dib-u-qaadashada sare, wuu qaadsiin karaa doofaarka caafimaadka leh wuxuuna xirayaa qaabilayaal aadanaha, wuxuuna sababi karaa cudurka zonotic.

News 02

Guudmarka hargabka avian ee EU-da, Maarso-Juun 2022

Hay'adda badbaadada cunnada ee Yurub, Xarunta Yurub ee Ka Hortagga iyo Xakamaynta Cudurka iyo Xakamaynta, Shaybaarka tixraaca Midowga Yurub ee hargabka Avian

PMID: 35949938; PMCID: PMC0356771; doi: 10.2903 / J.Efsa.022.7415

Sannadkii 2021-2022, infalawansada avian-ka ee aadka u sareeya ee cudurka loo yaqaan 'spian' Inta u dhaxaysa 16 Maarso iyo 10 Juun 2022, wadarta guud ee EU / ETA iyo Boqortooyada Ingiriiska 1 182 xaaladood oo ka mid ah ka go'itaanka digaagga (HA55 kiis), 410 xaaladood) iyo haad loo xilsaaro (22 xaaladood). Inta lagu gudajiro muddada dib u eegista, 86% dillaaca digaagga waxaa sabab u ahaa gudbinta HPaIV, iyadoo la xisaabin doono Faransiiska oo ka dillaacay digaagga guud ahaan digaagga guud ahaan 24% iyo waddamada kale ee kale ee ay saameeyeen wax ka yar 2% midkiiba. Jarmalka ayaa lahaa tirada ugu badan ee dillaaca shimbiraha duurjoogta ah (158 xaaladood), oo ay ku xigto Nederland (98 xaaladood) iyo Boqortooyada Midowday (48 xaaladood).

Natiijooyinka falanqaynta hidda-wadaha ayaa soo jeedinaya in HPAIV-ka uu hadda ku dhex jiro Yurub inta badan ay ka tirsan yihiin Spectrum 2.3.4 b. Tan iyo warbixintii ugu dambeysay, afar H5N6, laba H92 iyo laba H3N8 Infekshannada aadanaha ayaa laga soo sheegey Shiinaha iyo hal H5N1 Infekshinka aadanaha ayaa laga soo sheegey Mareykanka. Khatarta infekshinka waxaa loo qiimeeyay mid hoose oo ah dadka guud iyo kuwa hoose ilaa dhexdhexaad ee dadka ku sugan dadweynaha ee EU / EEA.

 Wararka 03

Dabeecadaha hadhaaga haraaga 127, 183 iyo 212 ee hanuuninta ha hidde ha

Antigenicicicicicicity, tadhigyada iyo cudur daynta H9N2 ee hargabka H9N2 Avian Avian

Mengalu taageere,Bing LIANG,Yongzhen zhao,Yaang zhang,Qingzheng Liu,Miao Tian,Yoqing zheng,Huisaathi Xia,Yassuo Suzuki,Xalan chen,Jiuhu Ping

PMID: 34724348; doi: 10.11111 / tbed.14363

Heerka H9N2 ee H9N2-ka ee hargabka avian viruska (AIF) waa mid ka mid ah noocyada ugu waaweyn ee saameeya caafimaadka warshadaha digaagga. Daraasaddan, laba nooc oo H9N2 ah oo hoosaadyo ah oo asal ahaan hidde ah laakiin antivicity, oo loo magacaabay a / is dil / 75 / JS / 2018) iyo JS / 76 (JS / 76), ayaa laga go'ay beerta digaagga. Falanqaynta isku xigxiga ayaa muujisay in JS / 75 iyo JS / 76 ay ku kala duwan yihiin seddex haraaga amino asino (127, 183 iyo 212) ee Haemagglutinin (ha). Si aad u sahamiso farqiga u dhexeeya guryaha bayoolaji ee u dhexeeya JS / 75 iyo JS / 76, lix fayras dib-u-dhac ayaa laga soo saaray iyada oo la adeegsanayo dariiqa hidda-wadaha ee Puertro Rico / 8/ PR8) sida silsiladda ugu weyn. Xogta laga soo qaado tijaabada digaagga iyo baaritaanada hidaydu waxay muujisay in R-76 / PR8 ay muujisay baxsashada antigen-ka ee ugu dhawaaqa ah sababtuna tahay isbedelada Amino acid ee jagooyinka 127 iyo 183 ee waallida Hano. Daraasado dheeri ah ayaa xaqiijiyey in Glycoseylaation in Glycoseylaation 'ee 127NN ay ka dhacday JS / 76 iyo isteats. DIIWAANGALINTA XUQUUQDA ASSASS waxay muujisay in dhammaan fayrasyada dib-u-dhigga, marka laga reebo mucjisooyinka aan yaraanin 127-da GlycOscylation-ka, si fudud loogu xirayo soo-dhoweynta aadanaha. Kobacyada koritaanka koritaanka iyo weerarada jiirka waxay muujiyeen in fayraska 127n-glycoskylated ay ku dartay wax yar oo ka yar unugyada A549 waxayna ka yaraayeen cudurka jir-ka-qaadista ee jiirka. Sidaa darteed, glycoslations iyo isbedelada amino acid ee wadaha ha hiddo-wadaha ah ee ha hidde ah ayaa mas'uul ka ah kala duwanaanshaha antianicicicicicicicicicicicicity iyo cudur dadaalka ah ee xudunta 2 H922.

Xigasho: Xarunta Xayawaanka Xayawaanka ee Shiinaha iyo Xarunta Epidemiology